Minimally Invasive Surgery and Interventional Techniques
Department of Biomechanical Engineering - Delft University of Technology
Dr.ir. Nick van de Berg
Researcher Delft University of Technology
BioMechanical Engineering
(+31)-15-2782054 Mekelweg 2
n.j.p.vandeberg@tudelft.nl 2628 CD, Delft
www.misit.nl Room F-0-200
Bio | Projects | Assignments

 

Biography

I’m passionate about developing new medical devices for optimal and personalised health solutions. This presents a mechanics-based counterpart of precision medicine (a term that is predominantly used in the field of genomics). Although personalised device design is in it’s infancy, the field is rapidly growing, e.g. think of patient-tailored 3D printed devices. A critical component in this field is the acquisition and integration of relevant clinical data. These can be obtained by medical images or via embedded sensors. In some cases, real-time adaptations are needed, resulting in true mechatronic device solutions with embedded sensors, actuators and (compliant) transmission mechanisms.

Personal pages: Research Gate - Google Scholar Linkedin - GitHub (MISIT)

Education & employment

  • 2020 - present: post-doc researcher, Erasmus MC, Department of Gynaecological Oncology.
  • 2016 - present: post-doc researcher, Delft University of Technology, Department of BioMechanical Engineering Faculty of Mechanical, Maritime, and Materials Engineering.
  • 2018 - 2020: post-doc researcher, Erasmus MC, Department of Radiology & Nuclear Medicine.
  • 2018: University Teaching Qualification (UTQ / BKO) completion.
  • 2017: Visiting Researcher, SINTEF - Department of Medical Technology, Norway.
  • 2015: Visiting Researcher, ACMIT - Austrian Center for Medical Innovation and Technology, Austria.
  • 2012 - 2016: PhD candidate, Delft University of Technology, Department of BioMechanical Engineering Faculty of Mechanical, Maritime, and Materials Engineering, thesis: Needle Steering Mechanics and Design Cases (oct 25, 2016), promotors Dr. John J. van den Dobbelsteen and Prof. dr. Jenny Dankelman.
  • 2011: Intern Leiden University Medical Center (LUMC), Department of Obstetrics.
  • 2008 - 2011: M.Sc. Biomedical Engineering, thesis: Soft tissue dissection with an ultrasonic snare and the quantification of thermal spread, advisor Dr. John van den Dobbelsteen

Sponsored or funded research projects

  • 2019: NWO Tech. for Oncology II - ARCHITECT Customised Needle Applicators, WP leader (725k€)
  • 2018: TTW Demonstrator - Steerable Needle for Percutaneous Interventions, co-applicant (149k€).
  • 2017: Delft HI - Customised Brachytherapy Applicators, project leader (25k€).
  • 2014: ZONmw IMDI - NAVIGATE Needles and image Guidance, assisting author (704k€).

Publications

  • de Lange D, van den Dobbelsteen JJ, Moelker A, van de Berg NJ, "Ultrasound-guided percutaneous liver biopsy: a review on obtaining adequate specimens", in J Med Devices, June 16 2020 (ASME).
  • Laan RC, Nout RA, Dankelman J, van de Berg NJ, "MRI-driven design of customised 3D printed gynaecological brachytherapy applicators with curved needle channels", in 3D Print Med, 5(8), pp 1-8, 2019 (Springer).
  • van de Berg NJ, Sánchez-Margallo JA, van Dijke AP, Langø T, van den Dobbelsteen JJ, "A methodical quantification of needle visibility and echogenicity in ultrasound images", in Ultrasound Med Biol, 45(4), pp 998-1009, 2019 (Elsevier).
  • de Jong TL, van de Berg NJ, Tas L, Dankelman J, van den Dobbelsteen JJ, "Needle placement errors: do we need steerable needles in interventional radiology?" Medical Devices (Auckl), 11:259-265, 2018 (Dovepress).
  • van de Berg NJ, Sánchez-Margallo JA, Langø T, and van den Dobbelsteen JJ, “Compliant joint echogenicity in ultrasound images: towards highly visible steerable needles”, in SPIE Medical Imaging: Image-Guided Procedures, Robotic Interventions, and Modeling, 105760X, pp 1-6, 2018 (SPIE).
  • van de Berg NJ, de Jong TL, van Gerwen DJ, Dankelman J, and van den Dobbelsteen JJ. "The influence of tip shape on bending force during needle insertion", in Sci Rep, 7:40477, pp 1-8, 2017 (Nature).
  • van de Berg NJ, Dankelman J, and van den Dobbelsteen JJ. "End-point accuracy in manual control of a steerable needle", in J Vasc Interv Radiol, 28(2), pp 276-283, 2017 (Elsevier).
  • Shahriari N, Roesthuis RJ, van de Berg NJ, van den Dobbelsteen JJ, Misra S. "Steering an Actuated-Tip Needle in Biological Tissue: Fusing FBG-Sensor Data and Ultrasound Images", in IEEE ICRA 2016 (IEEE Xplore).
  • Roesthuis RJ, van de Berg NJ, van den Dobbelsteen JJ, and Misra S. "Modeling and steering of a novel actuated-tip needle through a soft-tissue simulant using fiber bragg grating sensors", in IEEE ICRA 2015 (IEEE Xplore).
  • van de Berg NJ, Dankelman J, and van den Dobbelsteen JJ. "Design of an actively controlled steerable needle with tendon actuation and FBG-based shape sensing", in Med Eng Phys, 37(6), pp 617-22, 2015 (Elsevier).
  • van de Berg NJ, van Gerwen DJ, Dankelman J, and van den Dobbelsteen JJ. "Design choices in needle steering - a review", in Mechatronics IEEE/ASME T, 20(5), pp 2172-83, 2015 (IEEE Xplore).
  • van de Berg NJ, van den Dobbelsteen JJ, Jansen FW, Grimbergen CA, and Dankelman J. "Energetic soft-tissue treatment technologies: an overview of procedural fundamentals and safety factors", in Surg Endosc, 27(9), pp 3085-99, 2013 (Springer). 

Keynote / invited speaker

Refereed conference contributions

  • van de Berg NJ and van den Dobbelsteen JJ, "Ultrasound Image Analysis to Quantify Needle Visibility and Echogenicity", Bio-Medical Engineering Conference, Edgmond aan Zee, The Netherlands, 2019.
  • van de Berg NJ, Sánchez-Margallo JA, Langø T, and van den Dobbelsteen JJ, “Compliant joint echogenicity in ultrasound images: towards highly visible steerable needles”, in SPIE Medical Imaging: Image-Guided Procedures, Robotic Interventions, and Modeling, Houston, USA, 2018 (SPIE).
  • van de Berg NJ, Laan RC, Nout RA, "Custom-fit 3-D printed needle applicators for gynaecological brachytherapy", Design of Medical Devices Europe, Eindhoven, The Netherlands, 2017.
  • van de Berg NJ, Laan RC, Nout RA, "Additive manufacturing for gynaecological brachytherapy: custom-fit applicators based on MRI data", Society for Medical Innovation and Technology, Turin, Italy, 2017.
  • van de Berg NJ, Dankelman J, and van den Dobbelsteen JJ. "Evaluation of manual needle steering under image guidance", Bio-Medical Engineering Conference, Edgmond aan Zee, The Netherlands, 2017.
  • [Technical Exhibition] de Jong TL, van de Berg NJ, Tas L, van den Dobbelsteen JJ, "Steerable needles in radiologic liver interventions", Questionnaire & Exhibition at CIRSE conference, Barcelona, Spain, 2016.
  • van de Berg NJ, van den Dobbelsteen JJ. "Manual control of a tip articulated needle", Joint conference:  Society for Medical Innovation and Technology & Design of Medical Devices Europe, Delft, The Netherlands, 2016.
  • Shahriari N, Roesthuis RJ, van de Berg NJ, van den Dobbelsteen JJ, Misra S. "Steering an Actuated-Tip Needle in Biological Tissue: Fusing FBG-Sensor Data and Ultrasound Images", in IEEE ICRA, Stockholm, Sweden, 2016 (IEEE Xplore).
  • van de Berg NJ, van den Dobbelsteen JJ. "Shared-control system for inserting a tip-steered needle", Society for Medical Innovation and Technology, Brno, Czech Republic, 2015.
  • van de Berg NJ, van den Dobbelsteen JJ. "A hand-held actively steered needle for percutaneous interventions", Design of Medical Devices Europe, Wiener Neustadt, Austria, 2015.
  • van de Berg NJ, Roesthuis RJ, Misra S, and van den Dobbelsteen JJ. "Haptic shared control of a teleoperated steerable needle", World Haptics, Chicago, USA, 2015.
  • Roesthuis RJ, van de Berg NJ, van den Dobbelsteen JJ, and Misra S. "Modeling and steering of a novel actuated-tip needle through a soft-tissue simulant using fiber bragg grating sensors", in IEEE ICRA, Seattle, USA, 2015 (IEEE Xplore).
  • van de Berg NJ, Dankelman J, and van den Dobbelsteen JJ. "Active needle steering with visual and haptic feedback", Bio-Medical Engineering Conference, Edgmond aan Zee, The Netherlands, 2015.
  • van de Berg NJ, and van den Dobbelsteen JJ. "Tip-Steered Needle", DEMO in collaboration with Arkenbout EAA, "Using Kinect with 3Gear Systems software to control a tip-steered needle". Design of Medical Devices Europe, Delft, The Netherlands, 2014.
  • van de Berg NJ, and van den Dobbelsteen JJ. "Closed loop control of an actively steered needle with FBG-based shape feedback", Society for Medical Innovation and Technology, Shanghai, China, 2014.
  • van de Berg NJ, and van den Dobbelsteen JJ. "Robot-assisted needle steering by a cable driven tip actuator", Design of Medical Devices Europe, Delft, The Netherlands, 2013.
  • van de Berg NJ, and van den Dobbelsteen JJ. "Validation of a new tip actuated needle steering system", Society for Medical Innovation and Technology, Baden Baden, Germany, 2013.
  • van de Berg NJ, and van den Dobbelsteen JJ. "The design of a robotic actuator for flexible needle steering", Bio-Medical Engineering Conference, Edgmond aan Zee, The Netherlands, 2013.
  • Gahler MC, van de Berg NJ, Rhemrev J, Jansen FW, and van den Dobbelsteen JJ. "Vaginal Approach for Uterus Separation During Laparoscopic Hysterectomy", Design of Medical Devices, Minneapolis, USA, 2010
    • Abstract in Journal of Medical Devices, 2010 4(2) - Conference Abstracts 027514 (ASME).
  • Arkenbout EA, van de Berg NJ, Visser RJ, Schutte S, van der Helm, FCT, van den Bosch WA, and Simonsz HJ. "Eyelid pressure measurements for early diagnosis", The Association for Research in Vision and Ophthalmology, Fort Lauderdale, USA, 2008
    •  Abstract in Invest Ophthalmol Vis Sci, ARVO 2008 - E-Abstract 5265-A535 (IOVS).

Patents

  • van de Berg NJ, van den Dobbelsteen JJ, "Needle structure comprising a hollow cannula and a stylet", WO/2020/139083, 02.07.2020.

Teaching activities

  • 2017 - 2019: KT1000WI MATLAB exam design (with Dr. Ir. Arjo Loeve).
  • 2014 - 2018: BM41050 & BM1106 Applied Experimental Methods: Medical Instruments.
  • 2013: WB1630 Statics seminars.
  • 2013: WBP202 Haptic Experimental Design.
  • Graduate student supervision and committees:
    • Daily supervisor: Robin Straathof (TU Delft, 2020), Flip Somerwil (TU Delft, 2020), Danny de Lange (TU Delft, 2019), Ir. Daan van Duijn (TU Delft, 2019), Ir. Rianne Laan (TU Delft, 2017 - nomination IMDI talent price 2017-18), Jamie Erskine MSc (Uni of Glasgow 2016), Ir. Jordi Hogervorst (TU Delft, 2013), Ir. Ivana Nanut (TU Delft, 2013).
    • In committee: Ir. Amy Hoogenstraaten (TU Delft, 2019), Ir. Yanick Mampaey (TU Delft, 2019), Ir. Job Sanders (TU Delft, 2017), and others.
  • Coaching/supervising student groups (various BME minor / BSc final projects)

Media items

Demonstrators and lab set-ups

  • Personalised applicators for gynaecological brachytherapy

Personalised brachytherapy needle applicator

 

 Experimental set-up to study needle visibility for a large range of insertion angles.

 Hand-held steerable needle

Active tip-steered needle

  • Shared control set-up

 Shared control set-up

 

Last update: 01-05-2019

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