Minimally Invasive Surgery and Interventional Techniques Department of Biomechanical Engineering - Delft University of Technology

Prof.dr. Jenny Dankelman Full professor Delft University of Technology BioMechanical Engineering (+31)-15-2785565 Mekelweg 2 j.dankelman@tudelft.nl 2628 CD, Delft www.misit.nl Room 34-E1-260 Bio | Projects | Assignments Several projects in Nepal 06 May 2022  Projects together with a researcher in Nepal Fiber scope for anesthesia anesthesia, can it more sustainable 22 March 2021  How to redesign a disposable or reusable fiber scope so that they become more sustainable. Test and Calibration Methods for Devices in LMIC 19 March 2021  Appropriate Biomedical Test and Calibration Methods for LMIC Klepsparende aortawortel vervanging 01 March 2021  Aortaklep aandoening bij niet-oudere patiënten is meestal te wijten aan aortaworteldilatatie, leidend tot aortaklepinsufficiëntie. De aangewezen chirurgische therapie is in deze patienten het zogenoemde `klepsparende aortawortel vervangin Reducing environmental stress for the premature babies using smart foil 15 December 2020  In collaboration with a startup in the medical field, we would like to use smart foils to substitute the traditional covering methods for an incubator Predicting medical device failure in LMIC hospitals 27 November 2020  Predicting medical device failure, its impact on hospital’s mission, and optimal maintenance schedules for LMIC hospitals Modeling and Compensation of Hysteretic Nonlinearities in Robotic Catheters 06 October 2020  Modeling and Compensation of Hysteretic Nonlinearities in Robotic Catheters: Machine Learning Methods versus Mechanical Solutions 3D guidance for spinal surgery 16 September 2020  3D guidance for spinal surgery - Development of a DRS-enhanced drill Development of a bone tissue-simulating phantom 19 August 2020  Development of a bone tissue-simulating phantom for testing of a DRS-enhanced steerable drill A phantom simulating the fetal electrocardiogram 13 July 2020  The aim of the project is to develop a phantom that simulates the electrical activity of the fetal heart within the maternal abdomen. Developing a breast phantom to evaluate tumour margins assessment techniques 07 July 2020  Developing a breast phantom to assess different tumour margin assessment techniques during breast cancer surgery Learning using digital environments in Low- and Middle-Income Countries 17 November 2019  Motivating trainees and workers in using digital environments – learning to motivate across Low- and Middle-Income Country cultures Evaluation of ventilation of neonates in low resource settings 23 July 2019  Evaluation of medical equipment for low resource settings - Bubble Continuous Positive Airway Pressure – bCPAP Ear prosthesis for NEPAL 06 May 2019  Design and production of a simple ear prosthesis for ear patients in Nepal. Personalized brachytherapy applicators 07 February 2019  Preliminary studies to assess various facets for the development of personalized gynaecological brachytherapy applicators. Internships low resource settings 27 December 2018  Internships are available in Nepal, Suriname, Kenia and Indonesia Perfusion system for long term ex vivo perfusion of the liver 01 November 2018  A long term Ex Vivo Liver Perfusion system will be developed for a small animal able to control temperature and perfusate flow. Modulating liver regeneration 01 November 2018  Development of a perfusion model, enabling modulation and regeneration of the liver outside the body Tool to capture tumour cells circulating in blood 18 September 2018  With this tool it is aimed to make existing chemotherapies much more effective, as they can be more correctly prescribed Cleaning flexible endoscopes 18 September 2018  Internship at LUMC to determine the process steps needed to clean flexible endoscopes. The ARGUS Project 07 May 2018  Automatically Real time Generated early warning scoring system Using Sensor technology, a project from the department of Gynecology of the Erasmus MC Simulaties voor hartoperaties 01 May 2018  Help hartoperaties te verbeteren door een simulatiemodel te maken om calamiteiten te oefenen. Measuring the forces involved during stenting human diseased arterial vessels 29 March 2018  In this master project you will be involved in this important clinical challenge working towards the development of a test-bed that is capable of measuring the forces involved during stenting human disease arterial vessels. In particular, you will perform Invloed van een stenose op de ACCmax 20 March 2018  De afdeling Vaatchirurgie LUMC verricht onderzoek naar de invloed van stenoses met behulp van echo Duplex, in vitro flow-modellen en in vivo studies Internship in Suriname: Improve the current sterilization process in the Academic Hospital Paramaribo 16 November 2017  Internship in Suriname: Improve the current sterilization process in the Academic Hospital Paramaribo by analysing the current situation, identify the weaknesses and implementing pragmatic solutions. Intra-operatieve MRI bij neurochirurgische operaties; vernieuwde hoofd-fixatie en workflow. 11 July 2017  In dit project zal een nieuwe vorm van hoofdfixatie ontwikkeld worden en een bijbehorend planvoor optimale workflow voor het maken van een MRI scan tijdens de operatie. Design of a 3D Patient Specific Osteotomy 11 July 2017  This project relates to Patient Specific Osteotomy instruments that are designed using 3D visualisation techniques and manufactured using 3D printers. Interactieve database applicatie voor de gestructureerde behandeling van patiënten 03 July 2017  Ontwikkeling en implementatie van een interactieve database applicatie voor de gestructureerde behandeling van patiënten met inflammatoire darmziekten met biologicals Tracked tongue tumor surgery 15 June 2017  Intraoperative tracking of oral cavity carcinomas in head and neck surgery using MR-based three-dimensional (3D) models of surgical resections. Image guided surgery 15 June 2017  Intraoperative use of hyperspectral imaging in discriminating tumor from healthy tissue Platform for ultrasound guided oncological surgery - At Philips Research 05 April 2017  To improve the balance between radical surgery and preventing morbidity in cancer surgery, we aim to visualize a tumor marker with respect to the surgical instruments during oncological surgery. Heart Rate Variability as an indicator for intracranial pressure 03 April 2017  Prior research has shown that HRV can be used as an early indicator for Sepsis in Neonates, allowing antibiotics to start up to a day earlier. The Neurosurgical department of the Erasmus MC hospital is interested in testing if HRV can be used to monitor i Instrument guided removal of cement and 3D technology to improve total hip replacement. 14 November 2016  Aim: to develop an alternative approach to the extended trochanteric osteotomy by using instrument guided removal of cement and 3D technology. This will shorten the surgery, decrease blood loss, prevent fractures and reoperations. Internship in Academic hospital Suriname 23 June 2016  Sterilizing medical instruments is of the utmost importance in healthcare. Every hospital in the Netherlands has a ‘Centrale Sterilisatie Afdeling/Dienst’ which is responsible for the decontamination of the instruments, including cleaning, disinfection an Development of an organ incubator 07 June 2016  The aim of the project is to develop an organ incubator that will enable a significant improval of liver organs. Design of a robust and affordable electro surgical device for challenging low resource settings 27 May 2016  Electro surgery devices are used in the majority of surgeries in the developing world, but is also one of the most complex and burdensome devices. To overcome some of the problems of the electro surgery devices and make it appropriate for the use in chall Design of medical (surgical) equipment for challenging low resource settings 27 May 2016  For widespread implementation of surgery safe and high quality affordable equipment is needed that is appropriate for usage in challenging environments. The design has to encounter the local needs, able to deal with the lack of maintenance infrastructure, Contact and Friction between guidewire, catheter and blood vessel 17 May 2016  Experimental analysis to characterize the frictional forces and contact force between the guidewire and catheter and between the guidewire and vessels. Optical Coherence Tomography in a needle 28 April 2016  Goal of project is to develop a very thin needle that incorporates OCT technology. Thermal imaging in surgical procedures - Together with Philips 31 March 2016  Aim of this project is to develop techniques to monitor tissue perfusion and tissue/organ blood flow. Potential applications will be in monitoring organ perfusion upon resection in surgical procedures Smart electrosurgical instruments - Together with Philips 07 March 2016  Positive margins in tumor surgery remain a widespread problem in clinical practice.. The goal is to find out if optical techniques can be used to detect properties of coagulated tissue Assignments in St. Antoniusziekenhuis 28 September 2015  Several assignments in St. Antonius hospital Nieuwegein Ventilation in neonates 15 July 2015  Devopment of a new ventilation technique for too early born babies. Magnetically assisted video introducer for administering surfactant to preterm infants 15 July 2015  Design the smallest device for surfactant administration, which is magnetically steerable and video assisted. Wound flushing – Suction device for orthopedic revision surgery 14 July 2015  Developing a disposable flushing - suction system for orthopedic surgery that is not clogged by the debris that needs to be removed out of the wound. Plaque Mechanics 14 July 2015  Study the effect of mechanical stresses on initation, progression, destabilization and rupture of atherosclerotic plaques Temperature measurement for low-resources settings 14 July 2015  Philips Research is working on a portfolio of medical devices for low-resource settings. Improving tissue tracking on ultrasound movies of tendons in the wrist 14 July 2015  Measurement of tendon and nerve dynamics provides important insight into the (dys)function of the hand. We want to optimize imaging methods for reproducibility and robustness. Combined visualization of laparoscopic and volumetric X-ray images 25 September 2014  Use augmented reality images of tumors and nerves obtained from volumetric X-ray images (Philips XperCT) and combine them with laparoscopic images to determine for example structures below the surface which cannot be seen with the laparoscopy. Cerebral oxygenation in neonates: A sensitivity analysis of near infra-red spectroscopy 29 May 2013  The goal of this research is to determine the influence of parameters on the cerebral oxygenation, so that a model can be made to aid clinical decision. making. Unobtrusive monitoring for neonates in the neonatal intensive care unit 10 April 2013  Philips research is investigating unobtrusive sensing for the NICU, aiming for novel modalities that can be used to provide reliable measures, enabling children to recover faster. Master Internship at Urology department of the Erasmus MC 02 April 2013  This department aims at increasing the accuracy of the diagnosis of prostate cancer. Therefore fMRI and ultrasound images are combined. The focus of this assigment is to develop a steerable needle that allows for even higher accuracy. AMC in Amsterdam: Quantification of bladder deformation and tumor movement in radiotherapy of bladder cancer patients 22 March 2013  Radiotherapy for bladder cancer patients is performed on multiple days and the corresponding planning is made based on CT scans on the first day. However, the anatomy of the patient changes during the treatment, for example due to filling of the bladder. Eye surgery 05 December 2012  To increase the success of cornea transplantation, knowledge of the properties of the cornea membranes is essential. In this assignment the influence biomechanical properties on surgical outcome will be investigated. Internships / stageplekken 26 August 2012  An incomplete list of internship opportunities in hospitals, companies and universities. Vering in patient specifiek knie mechanisme 22 August 2012  Verbeter het ontwerp van een patient specifiek knie mechanisme en ontwerp er vering in. Home Publications Assignments Projects

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