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Minimally Invasive Surgery and Interventional Techniques
Department of Biomechanical Engineering - Delft University of Technology
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Dr.ir. Nick van de Berg
Prof.dr. Jenny Dankelman
Personalized brachytherapy applicators
26 October 2018

The image guided treatment of tumours by means of locally placed, radioactive sources, makes high dose rate (HDR) gynaecological brachytherapy (BT) a contemporary example of personalized care. The BT treatment quality depends on the ability to accurately place sources at a series of dwell positions. For most patients, an optimal dose distribution can be achieved by needle channels in an intracavitary applicator, sometimes supplemented by interstitial needles. 

 

The project involves the development of personalized needle applicators for gynaecological BT cancer treatment. Graduation assignments can be involve: 

  • Design of personalized (outer geometry as well as internal catheter channels) 3-D printed prototypes,
  • Comparison and assessment of currently used devices in MRI,
  • Optimization of workflow in collaboration with the LUMC,
  • Design of a test setup from phantom material, based on MRI.
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